Rena Fragiadaki
Experienced Technicians,
Haemopoiesis Research Laboratory
School of Medicine, University of Crete
Tel: (+30) 2810-394629
Email: fragiada@med.uoc.gr
EDUCATION
BSc, Biochemistry (2000), School of Environment and Life Sciences, University of Salford, Manchester, UK
PhD candidate, Laboratory of Clinical Bacteriology, Parasitology, Zoonoses & Geographical Medicine, School of Medicine, University of Crete, Greece
RESEARCH INTEREST
Investigation of DUFFY/DARC polymorphism in patients with neutropenia
POSITION
Experienced Technician/ Lab assistant in the Haemopoiesis Research Laboratory, School of Medicine, University of Crete, Greece
Staff member of the Public Cord Blood Bank
SELECTED PUBLICATIONS
The resveratrol analogue, 3,4,5,4'‑trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action. Androutsopoulos VP, Fragiadaki I, Spandidos DA, Tosca A. Int J Oncol. 2016: 1305-14
Synthesis and biological evaluation of trifluralin analogues as antileishmanial agents. Esteves MA, Fragiadaki I, Lopes R, Scoulica E, Cruz ME. Bioorg Med Chem. 2010: 274-81
KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitro. Krasagakis K, Fragiadaki I, Metaxari M, Krüger-Krasagakis S, Tzanakakis GN, Stathopoulos EN, Eberle J, Tavernarakis N, Tosca AD. J Cell Physiol. 2011: 1099-109
Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4'-tetramethoxystilbene (DMU-212) in human melanoma cells. Androutsopoulos VP, Fragiadaki I, Tosca A. Exp Dermatol. 2015: 632-4
Design and synthesis of potent antileishmanial cycloalkylidene-substituted ether phospholipid derivatives. Calogeropoulou T, Angelou P, Detsi A, Fragiadaki I, Scoulica E. J Med Chem. 2008: 897-908
The role of endothelial cell apoptosis in the effect of etanercept in psoriasis. Avramidis G, Krüger-Krasagakis S, Krasagakis K, Fragiadaki I, Kokolakis G, Tosca A. Br J Dermatol. 2010: 928-34
Structure-activity relationships of antineoplastic ring-substituted ether phospholipid derivatives. Papazafiri P, Avlonitis N, Angelou P, Calogeropoulou T, Koufaki M, Scoulica E, Fragiadaki I. Cancer Chemother Pharmacol. 2005: 261-70
EDUCATION
· BSc, Biochemistry (2000), School of Environment and Life Sciences, University of Salford, Manchester, UK
· PhD candidate, Laboratory of Clinical Bacteriology, Parasitology, Zoonoses & Geographical Medicine, School of Medicine, University of Crete, Greece
RESEARCH INTEREST
· Investigation of DUFFY/DARC polymorphism in patients with neutropenia
POSITION
· Experienced Technician/ Lab assistant in the Haemopoiesis Research Laboratory, School of Medicine, University of Crete, Greece
· Staff member of the Public Cord Blood Bank
SELECTED PUBLICATIONS
The resveratrol analogue, 3,4,5,4'‑trans-tetramethoxystilbene, inhibits the growth of A375 melanoma cells through multiple anticancer modes of action. Androutsopoulos VP, Fragiadaki I, Spandidos DA, Tosca A. Int J Oncol. 2016: 1305-14
Synthesis and biological evaluation of trifluralin analogues as antileishmanial agents. Esteves MA, Fragiadaki I, Lopes R, Scoulica E, Cruz ME. Bioorg Med Chem. 2010: 274-81
KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitro. Krasagakis K, Fragiadaki I, Metaxari M, Krüger-Krasagakis S, Tzanakakis GN, Stathopoulos EN, Eberle J, Tavernarakis N, Tosca AD. J Cell Physiol. 2011: 1099-109
Activation of ERK1/2 is required for the antimitotic activity of the resveratrol analogue 3,4,5,4'-tetramethoxystilbene (DMU-212) in human melanoma cells. Androutsopoulos VP, Fragiadaki I, Tosca A. Exp Dermatol. 2015: 632-4
Design and synthesis of potent antileishmanial cycloalkylidene-substituted ether phospholipid derivatives. Calogeropoulou T, Angelou P, Detsi A, Fragiadaki I, Scoulica E. J Med Chem. 2008: 897-908
The role of endothelial cell apoptosis in the effect of etanercept in psoriasis. Avramidis G, Krüger-Krasagakis S, Krasagakis K, Fragiadaki I, Kokolakis G, Tosca A. Br J Dermatol. 2010: 928-34
Structure-activity relationships of antineoplastic ring-substituted ether phospholipid derivatives. Papazafiri P, Avlonitis N, Angelou P, Calogeropoulou T, Koufaki M, Scoulica E, Fragiadaki I. Cancer Chemother Pharmacol. 2005: 261-70