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EDUCATION:
- BSc, Medical Biochemistry (2003), School of Medicine, University of Thessaly, Greece
- PhD, Stem Cell Biology (2009), Nuffield Department of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, UK
RESEARCH INTERESTS:
- Haemopoietic Stem Cells, Endothelial Progenitor Cells, Mesenchymal Stem Cells derived either from adult or embryonic sources and Investigation of their Action Mechanisms on Angiogenesis
- Molecular Erythropoiesis and Transcription Factor Functions in Gene Regulation and Chromatin Architecture Reorganization
- Targeted NGS in haematological malignancies, Idiopathic Neutropenias of Undetermined significance
CURRENT POSITION:
Key Personnel, Unit of Precision Medicine Crete, Hellenic Precision Medicine Network in Oncology
SELECTED PUBLICATIONS:
- Khoo CP, Roubelakis MG, Schrader JB, Tsaknakis G, Konietzny R, Kessler B, Harris AL, Watt SM. miR-193a-3p interacts with HMGB1 to regulate human endothelial cell function. Scientific Reports. 2017; 7:44137.
- Newey SE*, Tsaknakis G*, Khoo CP, Athanassopoulos T, Camicia R, Zhang Y, Grabowska R, Harris AL, Roubelakis MG, Watt SM. The Hematopoietic Chemokine CXCL12 Promotes Integration of Human Endothelial Colony Forming Cell-Derived Cells into Immature Vessel Networks. Stem Cells Dev. 2014 15; 23(22):2730-2743. (*Joint first authors)
- Papadakis M, Hadley G, Xilouri M, Hoyte LC, Nagel S, McMenamin MM, Tsaknakis G, Watt SM, Drakesmith CW, Chen R, Wood MJ, Zhao Z, Kessler B, Vekrellis K, Buchan AM. Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy. Nat Med. 2013; 19(3):351-357.
- Roubelakis MG*, Tsaknakis G*, Pappa KI, Anagnou NP, Watt SM. Spindle shaped human mesenchymal stem/stromal cells from amniotic fluid promote neovascularization. PLoS One. 2013;8(1):e54747. (*Joint first authors)
- Athanassopoulos A*, Tsaknakis G*, Newey SE, Harris AL, Kean J, Tyler MJ and Watt SM. Microvessel Networks in Pre-formed in Artificial Clinical Grade Dermal Substitutes in vitro using Cells from Haematopoietic Tissues. Burns. 2012; 38(5):691-701. (*Joint first authors)
- Zhou B*, Tsaknakis G*, Coldwell KE, Khoo CP, Roubelakis MG, Chang C, Pepperell E, Watt SM. A Novel Function for the Haemopoietic Supportive Murine Bone Marrow MS-5 Mesenchymal Stromal Cell Line in Promoting Human Vasculogenesis and Angiogenesis. Br J Haematol. 2012; 175(3);299-311. (*Joint first authors)
- Walker NG, Mistry A, Smith LE, Eves P, Forster S, Tsaknakis G, Watt S, Mac Neil S. A Chemically-defined Carrier for the Delivery of Human Mesenchymal Stem/Stromal Cells to Skin Wounds. Tissue Eng Part C Methods. 2011; 18(2):143-155.